info

product name:

Itraconazole

cas No. :

84625-61-6

MF :

C35H38Cl2N8O4

MW :

705.63

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Detail

Quick Details

Synonyms:

Sporanox;

Itraconazol;

Oriconazole;

Itraconazolum;

2-Butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-yl methyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one

Molecular structure:

Properties

Item

Specifications

Results

Appearance

White to almost white power

White powder

Melting range

166-170℃

168-170℃

Loss on drying

≤0.50%

0.36%

Residue on ignition

≤0.10%

0.07%

Assay

≥98.5%

99.2%

Conclusion

The results conforms with enterprise standards

 

Description

Itraconazole is an imidazole antifungal drug of the triazole ring. By preventing the activation of cytochrome P-450 including oxidase and peroxidase, 14, α-methyl sterol can not be dehydrogenated, can not be converted to ergosterol, so that the growth and proliferation of fungi is inhibited, and it has strong lipophilicity. It can pass through the biofilm to inhibit the binding of the membrane to the fungus. Its antibacterial spectrum is similar to ketoconazole. It is effective for superficial mycosis such as vaginal and oral candidiasis, skin mycosis, etc., and is expected to be an effective and safe drug for deep fungal infections such as cryptococcal encephalitis (AIDS). Used for vulvovaginal candidiasis caused by sensitive fungi, pityriasis and dermatophytosis.

Packaging

As your requirements

Storage

Store in a dry, well-ventilated place away from direct sunlight.

COA,

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