info

product name:

1,3-Bis(2,4-diaminophenoxy)propane tetrahydrochloride

cas No. :

74918-21-1

MF :

C15H24Cl4N4O2

MW :

434.19

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Detail

Quick Details

Synonyms:

1,3-Bis(2,4-diaminophenoxy)propane 4HCl

Molecular structure:

Properties

Item

Specifications

Appearance

White to off-white powder

Assay

≥99%

 

Description

1,3-Bis(2,4-diaminophenoxy)propane tetrahydrochloride, also known as 1,3-Bis(2,4-diaminophenoxy)propane 4HCl, is mainly used as an intermediate for hair dyes.

Usage amount

1,3-Bis(2,4-diaminophenoxy)propane tetrahydrochloride is the hydrochloride form of 1,3-Bis(2,4-diaminophenoxy)propane, which is a hair dye for cosmetics. According to the "Cosmetic Safety Technical Specification" (2015 Edition), its maximum allowable concentration when used in oxidative hair dye products is 1.0% (calculated as free radicals), and the maximum allowable concentration when used in non-oxidative hair dye products It is 1.2% (based on free radicals). According to the evaluation results of the European Union SCCP/1098/07, the maximum allowable concentration of 1,3-Bis(2,4-diaminophenoxy)propane tetrahydrochloride in both oxidized and non-oxidized hair dye products is 1.8% (based on 1,3-double -(2,4-Diaminophenoxy)propane tetrahydrochloride, the corresponding free radical concentration is 1.2%).

Solubility

The solubility data at room temperature are as follows:

Water: >100 g/L; ethanol: <1 g/L; DMSO: 10-100 g/L

Safety

The known safety data are as follows:

Acute toxicity:

Oral: Wistar Rat-LD50: 3570 mg/kg

Skin irritation:

After 0.5g of undiluted 1,3-Bis(2,4-diaminophenoxy)propane tetrahydrochloride was applied to rabbit skin for 1 hour, mild erythema appeared, no edema was observed, no corrosiveness to the skin, no systemic toxicity Or a fatal situation occurs.

Mucosal irritation:

1,3-Bis(2,4-diaminophenoxy)propane tetrahydrochloride is irritating to rabbit eyes, such as red eyes, conjunctival edema, and secretion.

In addition, 1,3-Bis(2,4-diaminophenoxy)propane tetrahydrochloride may cause allergic reactions.

Packaging

25kg/drum

Storage

Store in a dry, well-ventilated place away from direct sunlight.

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