info

product name:

Guanidine thiocyanate

cas No. :

593-84-0

MF :

CH5N3.CHNS

MW :

118.16

Taian, China

9/F,E-commerce Industrial Park

+86 156 6659 0861

Mon to Fri 8am to 6 pm

sales@taiangreenindustry.com

Send us your inquiry anytime!

Detail

Quick Details

Synonyms:

GTC;

GuSCN;

Guanidinium thiocyanate;

Guanidinium isothiocyanate;

Guanidine monothiocyanate

Molecular structure:

Properties

Item

Specifications

Results

Appearance

White crystalline powder

Conforms

Assay

≥99.5%

99.8%

Ammonium

≤0.20%

0.1%

Moisture

≤0.50%

0.26%

Ash

≤0.30%

0.17%

Melting point

118~121℃

118.6~120.3℃

PH

5.0~7.0

6

Cd

≤5mg/kg

<5mg/kg

Co

≤5mg/kg

<5mg/kg

Cr

≤5mg/kg

<5mg/kg

Cu

≤5mg/kg

<5mg/kg

Fe

≤5mg/kg

<5mg/kg

Mg

≤5mg/kg

<5mg/kg

Mn

≤5mg/kg

<5mg/kg

Ni

≤5mg/kg

<5mg/kg

Pb

≤5mg/kg

<5mg/kg

DNase

Not detected

Not detected

RNase

Not detected

Not detected

Protease

Not detected

Not detected

Conclusion

The results conforms with enterprise standards

 

Guanidine thiocyanate uses

Guanidine thiocyanate, also known as GTC and guanidinium thiocyanate, is mainly used in biomedicine, chemical reagents, etc., as a chaotropic agent and a strong denaturing agent for denaturation of lysed cells; extraction of RNA and DNA. As a DSSC adsorbent, guanidine thiocyanate can improve DSSC conversion.

Guanidine thiocyanate pH

The pH of 4% guanidine thiocyanate solution is 5.0~7.0.

Guanidine thiocyanate vs guanidine hydrochloride

Guanidine thiocyanate (guanidinium thiocyanate) and guanidine hydrochloride are both protein denaturants. Guanidine thiocyanate (guanidinium thiocyanate) is a more potent protein denaturant than guanidine hydrochloride. It is usually used to eliminate RNase activity when isolating intact ribonucleic acid.

Guanidine thiocyanate on skin

Guanidine thiocyanate (guanidinium thiocyanate) is harmful to human skin, so it is necessary to wear a laboratory suit when conducting experiments to avoid direct contact with guanidine thiocyanate (guanidinium thiocyanate).

Guanidine thiocyanate contamination

Guanidine thiocyanate (guanidinium thiocyanate) has little effect on the A260 / A280 ratio, so it also has little effect on RNA quantification. However, its presence has a very large effect on the A260 / A230 ratio; when it contains 0.5% of pollutants, the A260 / A230 ratio is reduced to below 0.5. Avoid using samples containing suspected guanidine contamination, as this will have a deleterious effect on downstream enzymatic reactions.

Guanidine thiocyanate toxicity

Hazard class and label elements of the product according to GHS (the seventh revised edition):

> GHS Hazard Class

Acute Toxicity - Oral                    Category 4

Guanidine thiocyanate solubility

2g/50ml in Water

Guanidine thiocyanate DNA extraction protocol

According to reports and research, the phenol-lithium chloride method can simultaneously extract RNA and DNA. It splits cells by phenol and SDS, denatures, depolymerizes proteins, inhibits RNase, and protects DNA with EDTA, and finally separates DNA and RNA according to the different precipitation speed of RNA and DNA in Li +. The entire process is completed within 2 hours.

Guanidine thiocyanate-phenol-chloroform extraction protocol

They can work together to inhibit RNase, and at the same time, the protein mutates under the joint action of guanidine thiocyanate (guanidinium thiocyanate) and sodium lauryl sarcosinate, thereby releasing RNA; under acidic conditions, the DNA rarely dissociates, the same protein A denaturation was precipitated, and RNA is on the upper layer.

Fast delivery

Our guanidine thiocyanate storage is usually about ten of tons, so it can be shipped within three working days of receiving the payment.

Stable price

Guanidine hydrochloride is an important raw material in guanidine thiocyanate synthesis. We are industrialized guanidine thiocyanate production, so we can keep guanidine thiocyanate price within a reasonable range.

Packaging

25kg/drum

Storage

Store in a dry, well-ventilated place away from direct sunlight.

Pls see the below guanidine thiocyanate coa and guanidine thiocyanate sds.

COA,

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