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Quick Details




Molecular structure:





White crystalline powder



Melting point








Bronopol, also known as 2-Bromo-2-nitro-1,3-propanediol. It is a white crystalline powder at room temperature. It is easily soluble in water, ethanol, propylene glycol, ethyl acetate, etc., slightly soluble in oil, and hardly soluble in chloroform, acetone, etc. Bronopol is slightly hygroscopic and is stable under normal conditions of storage. It is unstable in aluminum containers and stable in tin containers.


Bronopol is a new broad-spectrum and highly effective non-oxidizing industrial fungicide containing organic bromine, used to prevent the growth and reproduction of bacteria and algae in industrial circulating cooling water, lubricating oil for metal processing, paper pulp, wood, paint and plywood. At the same time, Bronopol can be used as a slime control agent, which is widely used in paper mill pulp and circulating cooling water systems. As a broad-spectrum and high-efficiency fungicide, Bronopol can quickly penetrate the cell membrane of microorganisms and act on certain protein groups, so that the normal redox of the cell is terminated, causing cell death. At the same time, its branch can also selectively bromide or oxidize the special enzyme metabolites of microorganisms, which eventually leads to the death of microorganisms. Bronopol can also be used as a preservative in cosmetics. It is added to shampoos, balsams, creams and other cosmetics during processing, with a concentration of 0.01%-0.02%. It can also be used in detergents and fabric treatment agents. As a bactericide, Bronopol can effectively control a variety of phytopathogenic bacteria, and is used as a seed treatment agent. The treatment of cotton seeds can prevent cotton black arm disease and bacterial rot caused by cotton leaf spot pathogen, and has no phytotoxicity to cotton. Bronopol can also be used for rice seedling disease. The use concentration is 800~1000mg/L.

Development History

Bronopol is effective against a wide range of plant pathogenic bacteria and is mainly used as a seed treatment agent. In addition, because of its broad-spectrum antibacterial properties, it was used as a disinfectant in the 1960s in medicine. With the increasing development of cosmetics, coupled with the broad-spectrum antibacterial properties of bronopol and good water solubility, it entered the late 1980s and was used as a cosmetic preservative and developed extremely rapidly. In recent years, bronopol has been widely used in feed, paint, fur anti-corrosion, air-conditioning circulating water bacteriostasis, oilfield water injection bacteriostasis and aircraft, vehicle and ship disinfection, etc., and the demand has rapidly increased.

As a broad-spectrum antibacterial agent of bromonitro alcohols, bronopol has the following characteristics:

Bronopol has a broad spectrum of antibacterial activity. It has effective antibacterial activity in the pH range of 4 to 9, in emulsion products containing surfactants, and in the formulation of high-concentration protein substances, especially for antibacterial activity. Strong Pseudomonas aeruginosa has special effects.

Bronopol is non-toxic, non-irritating and non-allergenic. The amount used in cosmetics is 0.01% to 005%. The toxicity test results show that bronopol is safe and is one of the cosmetic preservatives approved by the US FDA. Synergy.

Bronopol has good peeling performance, no foam when used, and can be miscible with water in any proportion in the liquid state.

Bronopol can be used in combination with a variety of surfactants, it has good stability and is not easy to decompose.

Bronopol has the characteristics of non-volatile, non-irritating odor, non-corrosive.


Bronopol can be used in a wide range of pH, from the acidic to the neutral range. It is unstable under high temperature and alkaline conditions, and becomes darker under the sunlight. It can be compatible with most surfactants, but when the materials containing -SH groups in cosmetic raw materials, such as cysteine, will reduce its antibacterial activity. In addition, aluminum metal can also reduce the antibacterial activity of bronopol.


The general additive amount is 0.2-0.5‰, and the maximum allowable additive amount in daily chemical products is 1‰. There is no residue in the discharge, and it will not cause cumulative pollution to the environment. Operating pH range: 4-9. Operating temperature range: generally dissolve in appropriate amount of water in advance and add below 60℃.




Store in a dry, well-ventilated place away from direct sunlight.