info

product name:

Safinamide Mesylate

cas No. :

202825-46-5

MF :

C17H19FN2O2.CH4O3S

MW :

398.45

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Detail

Safinamide Mesylate  Quick Details

 

Product name:Safinamide mesylate

Synonyms:(S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]propanamide methanesulfonate;(S)-(+)-2-[[4-(3-Fluorobenzoxy)benzyl]amino]propanamide;FCE26743;PNU151774E,NW1015;EMD1195686;2S-[[[4-[(3-fluorophenyl)methoxy]phenyl]methyl]amino]-propanamide, monomethanesulfonate

CAS No.:202825-46-5

MF:C17H19FN2O2.CH4O3S

MW:398.45

Molecular structure:

Appearance:White to off-white powder

Assay:≥98%

 

Safinamide Mesylate  Properties

Item

Specifications

Results

Appearance

White to off-white powder

White powder

Assay

≥98%

98.6%

Conclusion

The results conforms with enterprise standards

 

Safinamide Mesylate  Usage

Safinamide mesylate is the methanesulfonic acid form of its active component safinamide, a selective and reversible monoamine oxidase B (MAO-B) inhibitor with the value of 50% inhibition concentration IC50 of 98 nM. Having been used for the treatment of Parkinson’s disease (PD), safinamide potently modulates dopamine (DA), a substrate of MAO-B, suppressing DA uptake and reversibly binds to MAO-B blocking the function of MAO-B, which lead to the relief of PD symptoms. Besides MAO-B inhibition, safinamide exhibits novel anticonvulsant activities, including sodium channel blockade, calcium channel blockade and glutamate release inhibition, with values of IC50 of 8.2 μM, 31.5 μM and >56.4 μM respectively.

Safinamide Mesylate  Packaging

As your requirements

Safinamide Mesylate  Delivery

within 5~7 days

Safinamide Mesylate  Storage

Store in a dry, well-ventilated place away from direct sunlight.

COA , TDS ,